Researchers of the SFB recently discovered a new and exciting feature within the interplay between T-cell receptor and adhesion-mediated signaling.  Biochemical and imaging technolgies revealed an important function of two independent ADAP/SKAP55-modules for the CCR7-mediated activation of the integrin LFA-1. The data help explaining the role and diversity of molecules involved in the intracellular events upon T-cell activation. Details can be found here: http://www.ncbi.nlm.nih.gov/pubmed/22117043