Veröffentlichungen

Veröffentlichungen wissenschaftlicher Arbeiten zu Tumoren des Nervensystems von Mitgliedern des Hirntumor-Referenzzentrums

1. Firsching, R., Frowein, R.A., Nittner, K., Müller, W.: Raumforderungen im Conus-Cauda-Bereich - außer Bandscheiben. Nervenarzt 56, 200-205, 1985
2. Firsching, R., Schröder, R., Frowein, R.A., Köning, W.: Abtropfmetastase beim cerebralen Glioblastom/ Gliosarkom. Nervenarzt 56, 629-634, 1985
3. Richard, K.E., Knipprath, R., Godehardt, E., Herr-mann, H., Firsching, R.: The influence of intracranial pressure and clinico-neurological findings on outcome in patients with diencephalic tumors. In: Intracranial pressure Vi, Eds.: Miller, J.D., Teasdale, G.M., Rowan, J.O., Galbraith, S.L., Mendelow, A.D.. Springer, Berlin, Heidelberg, New York, Tokyo, 691-694, 1986
4. Kochanek, S., Schröder, R., Firsching, R.: Hemangio-pericytoma of meninges. I. Histopathological variability and differential diagnosis. Zent. Bl. Neurochir. 47, 183-190, 1986
5. Schröder, R., Firsching, R., Kochanek, S.: Hemangio-pericytoma of meninges. II. General and clinical data. Zent. Bl. Neurochir. 47, 191-199, 1986
6. Afra, D., Müller, W., Slowik, F., Firsching, R.: Supratentorial lobar pilocytic astrocytomas: Report of 45 operated cases, including 9 recurrences. Acta Neuro-chir. (Wien), 81, 90-93, 1986
7. Loennecken, I., Müller, W., Firsching, R.: Topo-chemical demonstration of Zinc in meningiomas. Acta Neuropathol. (Berl.), 74, 81-83, 1987
8. Müller, W., Füsting, M., Firsching, R.: DNA pattern in choroid plexus papillomas. Zbl. Neurochir., 48, 102-105, 1987
9. Müller, W., Reifferscheidt, I., Firsching, R.: Onco-cytic transformation in choroid plexus papilloma. Light-microscopic study of two cases. Neuropat. Pol., 25, 205-209, 1987
10. Müller, W., Slowik, F., Firsching, R., Afra, D., Sanker, P.: Contribution to the problem of giant cell astrocytoma. Neurosurg. Rev., 10, 213-219, 1987
11. Sanker, P., Firsching, R., Frowein, R.A., Nanassis, K.: Clinical,CT-and MR- findings in spinal space occupying lesions. In: Advances in Neurosurgery 16, 196-200, 1988
12. Müller, W., Iffland, R., Firsching, R.: Atomic ab-sorption spectrometry studies on metals in primary brain tumors. Trace Elements in Medicine, Vol. 5, 3, 109-113, 1988
13. Firsching, R., Fischer, A., Peters, R., Thun, R., Klug, N.: Growth rate of incidental meningiomas. J. Neurosurg. 545-547, 1990
14. Müller, W., Iffland, R., Dortmann, P., Firsching, R.: Interaction of magnesium and calcium in meningioma. Zentralbl. Pathol. 139, 45-50, 1993
15. Müller, W., Iffland, R., Firsching, R.: Metals in Tumors of the Sellar Region. Zentralbl Neurochir 54, 143-147, 1993
16. Scholz, M., Müller, C., Gottschalk, J., Firsching, R., Harders, A., Füzesi, L.: Detektion von numerischen chromosomalen Aberrationen und intratumoralen Heterogenitäten mit der nicht radioaktiven chromosomalen in situ Hybridisation an Meningeomen. Verh. Dtsch. Ges. Path. 77, 426 , 1993
17. Firsching, R., Tieben, R., Schröder, R., Stützer, H.: Long-term prognosis of low grade astrocytoma. Zentralbl Neurochir 55, 10-15, 1994
18. Scholz, M., Firsching, R., Feiden, W., Breining H., Brechtelsbauer, D., Harders, A.: Gagel's granuloma in the pituitary stalk. Clinical Neurology and Neurosurgery 97, 164-166, 1995
19. Csécsei, G., Klug, N., Székely, G., Firsching, R., Christophis, P.: Multimodality electroneurophysiological findings in intra-axial and extra-axial lesions of the brain stem. Acta Neurochir (Wien) 137,48-53, 1995
20. Firsching, R.: Growth of Meningiomas. J Neurosurgery, 84, 150, 1996
21. Scholz, M., Gottschalk, J., Striepecke, E., Firsching, R., Harders, A., Füzesi, L.: Intratumorous heterogeneity of chromosome 10 and 17 in meningiomas using non-radioactive in situ hybridization. J Neurosurg Sci 40,1, 17-23, 1996
22. Dietzmann, K., v. Bossanyi, P., Warich-Kirches, M., Kirches, E., Synowitz, H., Firsching, R.: Immunohisto-chemical detection of vascular growth factors in angiomatous and atypical meningiomas, as well as hemangiopericytomas. Path Res Pract 193, 503-510, 1997
23. Kirches E., Oda Y., Von Bossanyi P., Diete S., Schneider T., Warich-Kirches M., Dietzmann K.Mdr1 mRNA expression differs between grade III astrocytomas and glioblastomas.Clin Neuropathol 1997; 16: 34-36.
24. Firsching, R., Klein, S., Rückert, A., Schneemilch, C.: Intraoperatives Neuromonitoring großer Tumoren des Porus acusticus internus. Leitsymptom: Hörstörung - Vertigo. Ärzteblatt Sachsen-Anhalt, 9, 17-34, 1998
25. Schneider, T., Kirches, E., Schröder, U., Firsching, R.: Efficacy of mitoxantron-nanoparticles in glioblastoma cell-cultures. J Neuro-Oncol. 39, 136, 1998
26. Schneider, T., Kirches, E., Schröder, U., Firsching, R.: Inhibition of tgf-ß2 expression and cell proliferation by antisense-oligonucleotides-nanoparticles in glioblastoma cell cultures. Zentbl. Neuroch. Suppl. 65, 1998
27. Schneider, T., Reinhold, D., Ansorge, S., Firsching, R.: Plasma concentraion of TGF-ß in patients with glioblastoma. J. Canc. Res. Clin. Onc. Suppl 124, 141, 1998
28. Firsching, R., Hanebeck, J.: Reconstruction and outcome in skull base destructing tumours. Skull base surgery 9,2, 14, 1999
29. Kirches E., Michael M., Woy C., Schneider T., Warich-Kirches M., Schneider-Stock R., Winkler K., Wittig H., Dietzmann K.Loss of Heteroplasmy in the Displacement Loop of Brain Mitochondrial DNA in Astrocytic Tumors.Genes, Chromosomes & Cancer 1999; 26: 80-83.
30. Kirches E., Scherlach C., Von Bossanyi P., Schneider T., Szibor R., Kutz E., Warich-Kirches M. and Dietzmann, K.MGMT- and P450 3A- inhibitors do not sensitize glioblastoma cell cultures against nitrosoureasClin Neuropathol 1999, 18: 1-8
31. Firsching R, Bondar I, Heinze HJ, Hinrichs H, Hagner T, Heinrich J, Belau A.Practicability of magnetoencephalography-guided neuronavigation.Neurosurg Rev. 2002 Mar;25(1-2):73-8
32. Firsching R, Synowitz HJ, Grimm C.Zentralbl Neurochir. 2003;64(4):151-8, Pitfalls in surgery of meningeomas of the free tentorial edge.
33. Schneider T, Sailer M, AnsorgeS, Firsching R and ReinholdDIncreased concentrations of Transforming Growth Factor b1 and b2 in the plasma of patients with glioblastomaJournal of Neuro-Oncology 2006;79(1): 61-65
34. Schneider T., Becker A., Ringe K., Reinhold A., Firsching R., & Sabel, B. ABrain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles. Journal of Neuroimmunology 2008; 195(1-2): 21-27.
35. Tapia-Pérez JH, Sanchez-Aguilar M, Schneider T.The role of statins in neurosurgery.Neurosurg Rev. 2010 Jul; 33(3):259-70
36. Schneider T, Mawrin C, Scherlach C, Skalej M, Firsching R:Gliomas in adults.Dtsch Arztebl Int 2010; 107(45): 799-807.
37. Al-Zabin M, Ullrich WO, Brawanski A, Proescholdt MARecurrent brain metastases from lung cancer: the impact of reoperation.Acta Neurochir (Wien). 2010 Nov; 152(11):1887-92.
38. Gehring S., Tapia-Pérez JH., Kirches E., Firsching R., Keilhoff G., Schneider Th., Mawrin Ch. (S T und M C gleichwertig)Cytotoxic effects of statins and thiazolidinediones on meningioma cellsJ Neurooncol. 2011 May; 102(3):383-93
39. Tapia-Pérez JH, Kirches E, Mawrin C, Firsching R, Schneider T.Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells.Cancer Chemother Pharmacol. 2011 May; 67(5):1193-201
40. Schulz S, Pauli SU, Schulz S, Händel M, Dietzmann K, Firsching R, Höllt V.Immunohistochemical determination of five somatostatin receptors in meningioma reveals frequent overexpression of somatostatin receptor subtype sst2A.Clin Cancer Res. 2000 May;6(5):1865-74
41. Kirches E., Michael M., Warich-Kirches M., Schneider T., Weis S., Krause G.,Mawrin C. und Dietzmann K.Heterogeneous tissue distribution of a mitochondrial DNA polymorphism in heteroplasmic subjects without mitochondrial disorders.J Med Genet 2001, 38: 312-317
42. Kirches E., Krause G., Warich-Kirches M., Weis S., Schneider T., Meyer-Puttlitz B., Mawrin C. und Dietzmann K.High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples.Int. J. Cancer 2001, 93: 534-538
43. Schneider, T., Gerhards, R., Kirches, E., Firsching, R.: Preliminary results of active specific immunization with modified tumor cell vaccine in glioblastoma multiforme. J Neuro-Oncol. 53, 39-43, 2001
44. Mawrin C, Diete S, Treuheit T, Kropf S, Vorwerk CK, Boltze C, Kirches E, Firsching R, Dietzmann K.Prognostic relevance of MAPK expression in glioblastoma multiforme.Int J Oncol. 2003 Sep;23(3):641-8
45. Mawrin C, Grimm C, von Falkenhausen U, Kirches E, Scherlach C, Kanakis D, Vorwerk C, Boltze C, Firsching R, Dietzmann K.Pineal epidermoid coinciding with pineocytoma.Acta Neurochir (Wien). 2003 Sep;145(9):783-7
46. Mawrin C, Schulz S, Pauli SU, Treuheit T, Diete S, Dietzmann K, Firsching R, Schulz S, Höllt V.Differential expression of sst1, sst2A, and sst3 somatostatin receptor proteins in low-grade and high-grade astrocytomas.J Neuropathol Exp Neurol. 2004 Jan;63(1):13-9
47. Mawrin C, Sasse T, Kirches E, Kropf S, Schneider T, Grimm C, Pambor C,Vorwerk CK, Firsching R, Lendeckel U, Dietzmann K.Different activation of mitogen-activated protein kinase and Akt signaling is associated with aggressive phenotype of human meningiomas.Clin Cancer Res. 2005, 11: 4074-82
48. Mawrin C, Schneider T, Firsching R, Wiedemann FR, Dietzmann K, Bornemann A, Romeike BF, Sellhaus B, von Deimling A.Assessment of tumor cell invasion factors in gliomatosis cerebri.J Neurooncol. 2005;73(2):109-15
49. Mawrin C, Kirches E, Diete S, Wiedemann FR, Schneider T, Firsching R, Kropf S, Bogerts B, Vorwerk CK, Kruger S, Dietzmann K.Analysis of a single nucleotide polymorphism in codon 388 of the FGFR4 gene in malignant gliomas.Cancer Lett. 2006, 239: 239- 245
50. Pelz AF, Klawunde P, Skalej M, Wieacker P, Kirches E, Schneider T, Mawrin CNovel chromosomal aberrations in a recurrent malignant meningioma.Cancer Genet Cytogenet. 2007 Apr 1;174(1):48-53
51. Romeike BF, Joellenbeck B, Stein H, Loddenkemper C, Hummel M, Firsching R, Mawrin C.Precursor T-lymphoblastic lymphoma within a recurrent pituitary adenoma.Acta Neurochir (Wien). 2008 Aug;150(8):833-6. Epub 2008 Jun 27
52. Kirches E, Steiner J, Schneider T, Vorwerk CK, Scherlach C, Holtkamp N, Keilhoff G, Eng C, Mawrin C.Lhermitte-Duclos disease caused by a novel germline PTEN mutation R173P in a patient presenting with psychosis.Neuropathol Appl Neurobiol. 2010 Feb;36(1):86-9.
53. Mawrin C, Wolke C, Haase D, Krüger S, Firsching R, Keilhoff G, Paulus W, Gutmann DH, Lal A, Lendeckel U.Reduced activity of CD13/aminopeptidase N (APN) in aggressive meningiomas is associated with increased levels of SPARC.Brain Pathol. 2010 Jan;20(1):200-10. Epub 2009 Feb 19
54. Haase D, Schmidl S, Ewald C, Kalff R, Huebner C, Firsching R, Keilhoff G, Evert M, Paulus W, Gutmann DH, Lal A, Mawrin C.Fatty acid synthase as a novel target for meningioma therapy.Neuro Oncol. 2010 Aug;12(8):844-54. Epub 2010 Feb

Buchbeitrag

1. Klug, N., Firsching R.,: Tumoren und Pseudotumoren der frontalen Schädelbasis. European Arch Oto-Rhino-Laryngol Springer  Suppl 1993/I, 187-203, 1993
2. Firsching, R., Funke, M., Schröder, R., Sanker, P., Klug, N.: Operative Approach and Prognosis of perisellar Skull Base destructing Tumors. In: Skull Base Surgery. ed.: M. Samii, Karger, 321-323, 1994
3. Firsching, R.: Frühergebnisse und Langzeitergebnisse bei knochenzerstörenden intra- und extrakraniellen Schädelbasistumoren. In:Schädelbasischirurgie. Hrsg.: R. Schmelzle. Al-Budoor Kunst Verlag, Syrien, Damaskus Salhani Institution, 2000
4. Professionelle neurologische und neurochirurgische Pflege. Raimund Firsching, Hans-Joachim Synowitz, Friedrich Wolf. Verlag Hans Huber Bern, Göttingen, Toronto, Seattle 1. Auflage 2003
5. Thomas Schneider, Brain Tumor Therapy with Antisense Oligonucleotides in Erdmann, Volker A.; Reifenberger, Guido; Barciszewski, Jan (Eds.): Therapeutic Ribonucleic Acids in Brain Tumors, Springer Dordrecht Heidelberg London NewYork, 2009