The Institute
Profile of the Institute
The Institute of Molecular and Clinical Immunology is involved in providing medical care to patients, in teaching and in immunological research.
The spectrum of clinical diagnostics includes the analysis of humoral and cellular components of the immune system during illness and therapy. Since 2004 the Institute for Molecular and Clinical Immunology was approved by the German Society of Immunology (DGFI) to train employees as "Fachimmunologin/Fachimmunologe" (consultant immunologist) according to the DFGI guidelines (German). The approval not only includes training in theoretical and basic immunology but also training in clinical diagnostics of allergic diseases, autoimmune diseases and immunodeficiencies. Within the Institute for Molecular and Clinical Immunology, Prof. Dr. med. B. Schraven, Prof. Dr. med. Dirk Reinhold and Dr. rer. nat. Annegret Reinhold are approved ("Fachimmunologen" and thus entitled to conduct the training program.
The teaching is addressed to students of the medical and biological faculties and consists of laboratory-based practical courses, lectures and seminars. A scientific seminar programme enables exchange of information with colleagues from national and international institutions.
The focus of research at our institute is on the elucidation of the molecular mechanisms of activation and differentiation of T cells and other hematopoietic and inflammatory cells. We investigate mechanisms of signal transduction, proteolysis and inflammation, cell death, celldynamic processes as well as Systems Biology of T cell activation. Another research focus consists of the development and employment of complex imaging methods to visualize immune processes.
As an additional imaging resource, the Core facility Multidimensional Microscopy and Cellular Diagnostics is based at the institute.

News
New Publication on TCR - Adhesion molecular interplay in the journal Blood
Researchers of the SFB recently discovered a new and exciting feature within the interplay between T-cell receptor and adhesion-mediated signaling. Biochemical and imaging technolgies revealed an important function of two independent ADAP/SKAP55-modules for the CCR7-mediated activation of the integrin LFA-1.
mehrSeminare
24.05.2012
LPS recognition and signaling in mast cells: it´s hip to be square
Univ.-Prof. Michael Huber
Institute of Biochemistry and Molecular Biology University Hospital Aachen
30.05.2012
Quantitative proteomics: from regulatory T cells to cellular programming
Dr. Markus Feuerer
DKFZ Heidelberg
Dr. Jeroen Krijgsveld
EMBL Heidelberg