Publications in 2006

Reiser, G., Schönfeld, P. and Kahlert, S.
Mechanism of toxicity of the branched chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.
Int. J. Dev. Neurosci. 24 (2006), 113-122.

Abstract

Tulapurkar, M., Zündorf, G. and Reiser, G.
Internalization and desensitization of a green fluorescent protein-tagged P2Y1 nucleotide receptor are differently controlled by inhibition of calmodulin-dependent protein kinase II.
J. Neurochem. 96 (2006), 624-634.

Abstract

Henrich-Noack, P., Striggow, F., Reiser, G. and Reymann, K.G.
Preconditioning with thrombin can be protective or worsen damage after endothelin-1-induced focal ischemia in rats.
J.Neurosci. Res. 83 (2006), 469-475

Abstract

Henrich-Noack, P., Rieck-Burchardt, M., Baldauf, K., Reiser, G. and Reymann, K. G.
Focal ischemia induces expression of protease-activated receptor 1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra.
Brain Res. 1070 (2006), 232-241.

Abstract

Nahum, V, Tulapurkar, M.E., Lévesque, S.A., Sévigny, J., Reiser, G. and Fischer, B.
Diadenosine- and Diuridine-Poly(borano)phosphate analogues: Synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2-Receptors.
J. Med. Chem. 49 (2006), 1980-1990.

Abstract

Schönfeld, P. and Reiser, G.
Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria
J. Biol. Chem. 281 (2006), 7136-7142.

Abstract

Luo, W., Wang, Y., Hanck, T., Stricker, R. and Reiser, G.
Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1.
J. Biol. Chem. 281 (2006), 7927-7936.

Abstract

Stricker, R., Chow, K. M., Walther, D., Hanck, T.; Hersh, L. B. and Reiser, G.
Interaction of the brain specific protein p42IP4/centaurin-a1 with the peptidase nardilysin is regulated by the cognate p42IP4 ligands of p42IP4, PtdIns(3,4,5)P3 and PtdIns(1,3,4,5)P4 with stereospecificity.
J. Neurochem. 98 (2006),343-354.

Abstract

Schönfeld, P., Kahlert, S. and Reiser, G.
A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and astrocytes isolated from rat brain.
Exp.Gerontol.41 (2006),688-696

Abstract

Wang, Y., Luo, W., Stricker, R. and Reiser, G.
Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1.
J.Neurochem. Vol.98 Issue 4 Page 1046 - August 2006

Abstract

Bunik, V.I., Raddatz, G., Wanders, R.J.A. and Reiser, G.
Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid.
FEBS Lett. 580 (2006), 3551-3557.

Abstract

Sharon, E., Lévesque, S.A., Munkonda, M.N., Sévigny, J., Ecke, D., Reiser, G. and Fischer, B.
Fluorescent N2, N3-e-adenine nucleoside and nucleotide probes: Synthesis, spectroscopic properties and biochemical evaluation.
ChembioChem. (2006)Volume 7, Issue 9 , Pages 1361 - 1374

Abstract

Strokin, M., Chechneva, O., Reymann, K. G. and Reiser, G.
Neuroprotection of rat hippocampal slices exposed to oxygen-glucose deprivation by enrichment with docosahexaenoid acid and by inhibition of hydrolysis of docosahexaenoid acid-containing phospholipids by calcium independent phospholipase A (2).
Neurosci. 140 (2006), 547-553.

Abstract

Laubinger, W., Tulapurkar, M.E., Schäfer, R. and Reiser, G
Distinct mono- and dinucleotide-specific P2Y receptors in A549 lung epithelial cells: different control of arachidonic acid release and nitric oxide synthase expression.
Eur. J. Pharmacol. Vol. 543, Issues 1-3 , 14, 08, 2006, Pages 1-7

Abstract

Schäfer, R., Hartig, R., Sedehizade, F., Welte, T. and Reiser, G.
Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kB1 and mitogen-activated protein kinase pathways.
FEBS J. 273 (2006) 3756-3767.

Abstract

Ecke D., Tulapurkar, M.E., Nahum, V., Fischer, B. and Reiser, G.
Opposite diastereoselective activation of P2Y1 and P2Y11 nucleotide receptors by adenosine 5’-O-(1-á-boranotriphosphate) analogues.
Br. J. Pharmacol. 149 (2006), 416-423.

Abstract

Wang,Y., Luo, W., Wartmann, T., Halangk, W., Sahin-Tüth, M. and Reiser, G
Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not protease-activated receptor 2, in rat astrocytes.
J. Neurochem. 99 (2006), 759-769.

Abstract

Reiser, G., Schönfeld, P. and Kahlert, S
Mechanism of toxicity of the branched chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.
Int. J. Dev. Neurosci. 24 (2006), 113-122.

Abstract