INTERNATIONAL CONFERENCE

 “CELLULAR SIGNALING IN NEUROPROTECTION AND PLASTICITY”

 September 26- 28, 2002

Haus 22
Otto-von-Guericke-Universität Magdeburg
Medizinische Fakultät Leipziger Str.44
39120 Magdeburg, Germany


Main organizer:
Prof. Dr. G. Reiser, Magdeburg		 Advisory board: 
Prof. Dr. R. Heumann, Bochum
Prof. Dr. R. Schliebs, Leipzig
PD Dr. G. Münch, Leipzig
Prof. Dr. C. Kaltschmidt, Witten

FINAL PROGRAM

Thursday, September 26th, 2002


             1:00 PM
 Registration and  Poster mounting
 (posters are displayed throughout the entire conference)
             1:45 PM
Welcome address

        Introduction: Georg Reiser (Speaker of the Study Group Neurochemistry)

Session I

chair: F. Hucho 


2:00 PM 
M. Norenberg 
 (Miami, USA)
Role of mitochondrial permeability transition in ammonia  neurotoxicity
Communications
Neurodegenerative and protective mechanisms I
2:45 PM
C. Culmsee
(Marburg, Germany)
Mechanisms of neuroprotection by p53 inhibitors
3:10 PM
G. Reiser 
(Magdeburg, Germany)
Long chain fatty acids: Neuroprotection through dampening Calcium signals - Neurodegeneration  by mitochondrial inhibition
3:30 PM
J. U. Frey 
 (Magdeburg, Germany)
The consolidation of hippocampal plasticity: associative, heterosynaptic and intracellular requirements

4:15 PM Coffee Break
 

Session II

chair: R. Schliebs 


Short communications
  Cytoskeleton, cell structure and receptors 
4:45 PM
                            M. M. Kessels
(Magdeburg, Germany)
 Mammalian Abp1 may function at the interface of endocytosis and the actin cytoskeleton in both pre- and postsynapses
5:00 PM
B. Qualmann 
(Magdeburg, Germany)
Syndapins and their binding partners, a functional inter-face between vesicle formation and actin cytoskeleton
5:15 PM
H.-G. Breitinger
(Erlangen, Germany)
Intracellular domains control activation and desensitisation of the inhibitory glycine receptor
5:30 PM
M. Blaabjerg 
(Odense, Denmark)
Changes in gene expression induced by activation of group I metabotropic glutamate receptors
5:45 PM
End of session II

Break
 
 
 

                                                                                                           chair: G. Reiser

  Keynote / public - lecture

                  6:00 PM
 
G. Fiskum  (Baltimore, U.S.A)

 Role of mitochondria in neural cell fate

 

7:15 PM    Welcome reception for the conference participants


 

Friday, September 27th, 2002

Session III

 chair: E. Gundelfinger


9:00 AM
M. Leist 
(Copenhagen, Denmark)
Caspase-independent mechanisms of cell elimination
Short communications 
  Neuroprotection - cellular and clinical aspects

 
9:45 AM
A.-L. Sirén 
(Göttingen, Germany)
Hematopoietic Growth Factors in the Brain: Neuroprotection in vitro 
10:00 AM
H. Ehrenreich
(Göttingen, Germany)
Erythropoietin: novel  clinical approach to neuroprotection in human brain disease
10:15 AM
O.G. Rössler 
(Homburg, Germany)
Neuroprotection of immortalized hippocampal neurons by Brain-derived neurotrophic factor – Role of extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase. 

10:30 AM Coffee Break

Session IV

chair: C. Kaltschmidt  

Short communications
Astrocytes and Oligodendrocytes
11:00 AM
 B. Ahlemeyer
(Münster, Germany)
 Activated astrocytes increase the susceptibility of neurons to glutamate by stimulation of protein kinase C
11:15 AM
M. L. Strokin 
(Magdeburg, Germany)
Regulation of docosahexaenoic and arachidonic acid release in rat astrocytes
11:30 AM
                         O. Goldbaum
(Oldenburg, Germany)
            Stress-induced  Tau  Modulation in                                      Oligodendrocytes
11:45 AM
A. W. Püschel
 (Münster, Germany)
Signal transduction by receptors for the repulsive axon guidance signal semaphorin 3A: the role of Rho-like GTPases

12:30 PM Lunch

Session V


             1:15 PM
Business meeting of study-group / Poster viewing
 
chair: J. Bartsch
2:00 PM
H. Lassmann
 (Wien, Austria)
Pathogenesis of inflammatory diseases of the nervous system and  neuronal inflammation
 Communications
Alzheimer and neurodegeneration
2:45 PM
I. Blasko 
(Innsbruck, Austria)
Interaction of the immune system with the amyloid beta peptide in Alzheimer’s disease
3:15 PM
G. Münch
(Leipzig, Germay)
Beta-Amyloid peptide potentiates inflammatory responses induced by LPS, interferon -gamma and "advanced glycation endproducts" in microglia 
3:45 PM
J. Apelt
(Leipzig, Germany)
         Expression of neprilysin, a putative    ß-amyloid-degrading enzyme, in transgenic              Tg2576 Alzheimer mouse brain  
4:00 PM
T. Züchner
(Magdeburg, Germany)
Differential control of expression of alpha -and beta -secretases through muscarinic acetylcholine  receptor signalling 

4:15 PM Coffee Break
Session VI

 chair: K. Reymann

4:45 PM
G. Xi
(Ann Arbor, USA)
Mechanisms of thrombin-induced tolerance to brain injury

                   5:30 PM                    Plenum poster presentation / discussion

                                                                chaired by G. Thiel (Homburg) and R. Heumann (Bochum)




               6:45 PM                    Bus transfer to Conference Dinner at "Damm-Mühle"

7:00 PM Dinner and Social Event

"Die Welt im leeren Raum – Otto-von-Guericke 1602-1686"
Magdeburger Kulturhistorisches Museum, Guided tour Quadri-centenary-Exhibition

 

Saturday, September 28th, 2002

 Session VII

chair: J. Zimmer 


9:00 AM
 E. Toescu 
(Birmingham, UK)
Dysregulation of calcium homeostasis in neuronal ageing: a metabolic perspective
Short communications
 Neurodegeneration and neuroprotective mechanisms II 
9:45 AM
                         J.H.M. Prehn
                      (Münster, Germany) 		      Modulation of apoptosis induced            by endoplasmic reticulum stress by               amyloid precuror protein 
10:05 AM
S. Roßner
(Leipzig, Germany)
Cloning and expression of the rat BACE1 promoter
10:20 AM
S. Vartiainen
(Kuopio, Finland)
  
Caenorhabditis elegans models of dopaminergic neuron degeneration 

10:35 AM Coffee Break

 Session VIII

chair: B. Hamprecht


Short communications
  Neurochemistry: Recent developments 
11:00 AM
M. Dreger
(Berlin, Germany)
 Mass Spectrometric Mapping of Proteins of the dorsal region of the spinal cord
11:15 AM
V. Horejschi,  B. Kaltschmidt (Witten, Germany)
Analysis of gene expression during cerebellum development
11:30 AM
J. Schwamborn 
(Münster, Germany)
Analysis of tumor necrosis factor induced gene expression - a role of nuclear factor kappa-B.
11:45 AM
J.-Y. Hwang 
(Jülich, Germany)
Calcium- and Myristoylation-dependent Properties of Guanylate Cyclase Activating Protein-1 
 and -2
12:00 PM
J. Strosznajder 
 (Warsaw, Poland)
The role of NO and PARP in molecular mechanism of brain ageing and  ischemia reperfusion pathology
 12:55 PM 
Concluding remarks
  
1:00 PM
End of  the meeting
  

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