Parent J, Ciampa C, Harrison TM, Adams J, Zhuang K, Betts MJ, Maass A, Winer JR, Jagust WJ, Berry AS (2022). Locus coeruleus catecholamines link neuroticism and vulnerability to tau pathology in aging. NeuroImage (accepted)

Costanzo E, Lengyel I, Parravano M, Gordon I, Biagini I, Veldsman M, Badhwar A, Betts M, Llewellyn D, Lourida I, MacGillivray T, RittmanT, Tamburin S, You Ta X, Virgili G (2022). Ocular biomarkers for Alzheimer's disease dementia: an umbrella systematic review. JAMA Opthalmology (in press)

Liebe T, Kaufmann J, Hämmerer D, Betts M, Walter M (2022). In vivo tractography of human locus coeruleus –relation to 7T resting state fMRI, psychological measures and single subject validity. Molecular Psychiatry (in press)

Ciampa CJ*, Parent JH*, Harrison TM, Fain RM, Betts MJ, Maass A, Winer J, Baker S, Janabi M, D’Esposito M, Jagust WJ, Berry AS (2022). Associations among locus coeruleus catecholamines, tau pathology, and memory in aging. Neuropsychopharmacology (in press)


Dünnwald M, Ernst P, Düzel E, Tönnies K, Betts MJ, Oeltze-Jafra S (2021). Fully Automated Deep Learning-based Localization and Segmentation of the Locus Coeruleus in Aging and Parkinson’s Disease using Neuromelanin-sensitive MRI. IJCARS; 16: 2129-2135

Ludwig M, Wienke C, Betts MJ, Zähle T, Hämmerer D. Current challenges in reliably targeting the noradrenergic Locus Coeruleus using transcutaneous auricular vagus nerve stimulation (taVNS). Auton Neurosci; 236

Doppler CE, Kinnerup M, Brune C, Farrher E, Betts MJ, Fedorova T, Schaldemose JL, Knudsen K, Ismail R, Seger A, Hansen AK, Stær K, FinkGR, Brooks DJ, Nahimi A, Borghammer P, Sommerauer M (2021). Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson’s disease. Brain 144: 2732-2744

Dünnwald M, Betts MJ, Düzel E, Oeltze-Jafra S (2021). Localization of the Locus Coeruleus in MRI via Coordinate Regression. Bildverarbeitung für die Medizin: 10-15


Betts MJ*, Richter A*, de Boer L, Tegelbeckers J, Perosa V, Bauman V, Chowdhury R, Dolan RJ, Schott B, Seidenbecher C, Düzel E, *Guitart-Masip M, *Krauel K. Learning in anticipation of reward and punishment: Perspectives across the human lifespan. Neurobiol of Aging 96: 49-57

Farmer AD, Strzelczyk A, Finisguerra A, Gourine AV, 31 others, Betts MJ, 28 others, Koenig J. International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020). Frontiers. Hum. Neurosci 14: 409

Young PNE, Estarellas M, Coomans E, Srikrishna M, Beaumont H, Maass A, Venkataraman A, Lissaman R, Jiménez D, Betts MJ, McGlinchey E, Berron D, O’Connor A, Fox N, Pereira J, Jagust W, Carter SF, Paterson RW, Schöll M. Imaging Biomarkers in Neurodegeneration: Current and Future Practices. Alzheimer’s Research Therapy 12: 1-17

Wackershauser V, Betts MJ, BrunnliebC, Apostolova I, Buchert R, Düzel E, GruendlerT, VogtB. Older adults show a reduced tendency to engage in context-dependent decision biases. Neuropsychologia 142: 107445

Ehrenberg AJ, KhatunA, Coomans E, Betts MJ, Capraro F, Thijssen E, Senkevich K, Bharucha T, Jafarpour M, Young PNE, Jagust W, Carter SF, Lashley T, Grinberg LT, Pereira JP, Mattsson N, Ashton NJ, Hanrieder J, Zetterberg H, Schöll M, Paterson RW. Relevance of biomarkers in different neurodegenerative diseases. Alzheimer’s Research Therapy 12: 1-12

Betts MJ, Henson RN, Düzel E, Rowe J, Cam-CAN, *Howard R, *Hämmerer D. Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences. Nature Communications 11: 1712-1721

Dünnwald M, Betts MJ, Sciarra A, Düzel E, Oeltze-Jafra S. Automated Segmentation of the Locus Coeruleus from Neuromelanin-Sensitive 3T MRI Using Deep Convolutional Neural Networks. Bildverarbeitung für die Medizin: 61-66

Perosa V, de Boer L, Ziegler G, ApostolovaI, Buchert R, Metzger C, AmthauerH, Guitart-Masip M, *Düzel E, *Betts MJ. The role of the striatum in learning to orthogonalize action and valence: a combined PET and 7T MRI aging study. Cerebral Cortex 2020;00: 1–12


Betts MJ, Kirilina E, Otaduy M, Ivanov D, Acosta-Cabronero J, Callaghan M, Lambert C, Pine K, Passamonti L, Loane C, Cardenas-Blanco A, Keuken M, Trujillo P, Ugurbil K, Lüsebrink F, Mattern H, Liu K, Priovoulos N, Fließbach K, Maaß A, Ehrenberg A, Speck O, Weiskopf N, Dolan RJ, Inglis B, Tosun D, Morawski M, Zucca F, Mather M, Heinsen H, Poser B, Howard R, Zecca L, Rowe J, Jacobs H, Grinberg L, *Düzel E, * Hämmerer D. Locus coeruleus imaging as a biomarker for noradrenergic dysfunction. Brain 142: 2558-2571

Betts MJ, Cardenas-Blanco A, Kanowski M, Spottke A, Teipel S, Kilimann I, Jessen F, Düzel E. Locus coeruleus MRI contrast is reduced in Alzheimer’s disease dementia and correlates with CSF Aß levels. Alzheimers Dement. Diagn. Assess. Dis. Monit 11: 281-285

Liu K, Acosta-Cabronero J, Cardenas-Blanco A, Loane C, Berry A, Betts MJ, Kievit R, Henson R, Düzel E, Cam-CAN, *Howard R, *Hämmerer D. In vivo visualisation of age related differences in the locus coeruleus. Neurobiol of Aging 74: 101-111


Düzel E, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Betts MJ, 33 others, Jessen F (2018). CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume. Alzheimers Dement. Diagn. Assess. Dis. Monit. 10: 782–790

Betts MJ, Ehrenberg A, Hämmerer D, Düzel E (2018). Commentary: Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice. Frontiers in Neuroscience 12: 401

Hämmerer D, Callaghan MF, Hopkins A, Kosciessa J, Betts MJ, Cardenas-Blanco A, Kanowski M, Weiskopf N, Dayan P, Dolan RJ, Düzel E (2018). Locus Coeruleus integrity in old age is selectively related to memories linked with salient negative events.

Proceedings of the National Academy of Sciences 115: 2228-2233


Betts MJ, Cardenas-Blanco A, Kanowski M, Jessen F, Düzel E (2017). In vivo MRI assessment of the human Locus Coeruleus along its rostrocaudal extent in young and older adults. Neuroimage 163: 150-159

Hämmerer D, Hopkins A, Betts MJ, Maaß A, Dolan RJ, Düzel E (2017). Emotional arousal and recognition memory are differentially reflected in pupil diameter responses during emotional memory for negative events in younger and older adults. Neurobiol of Aging 58: 129-139

Acosta-Cabronero J, Cardenas-Blanco A, Betts MJ, Butryn M, Valdes-Herrera JP, Galazky I, Nestor PJ (2017) .The whole-brain pattern of iron perturbations in early Parkinson’s disease. Brain. 140: 118-131


*Betts MJ, *Acosta-Cabronero J, Cardenas-Blanco A, Nestor PJ, Düzel E (2016). High-resolution in vivo characterization of the aging human brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 T. Neuroimage. 138: 43-63

Acosta-Cabronero J, Betts MJ, Cardenas-Blanco A, Yang S, Nestor PJ (2016). In vivo MRI mapping of brain iron deposition across the adult lifespan. J. Neurosci. 36(2):364-374

2010 – 2015

Düzel E, Guitart-Masip M, Maaß A, Hämmerer D, Betts MJ, Speck O, Weiskopf N, Kanowski M (2015). Midbrain fMRI: Applications, limitations and challenges. In book fMRI: From Nuclear Spins to Brain Functions. 581-609

Betts MJ, O’Neill M, Duty S (2012). Allosteric modulation of the group III mGlu receptor 4 provides functional neuroprotection in the rodent 6-OHDA model of Parkinson’s disease. Br. J. Pharmacol. Aug;166(8):2317-30

Broadstock M, Austin P, Betts MJ, Duty S (2012). Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata.  Br. J. Pharmacol. Feb;165(4b):1034-45

*Austin P, *Betts MJ, *Broadstock M, O’Neill M, Mitchell S, Duty S (2010). Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson’s disease. Br. J. Pharmacol. Aug;160(7):1741-5

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