Startseite
Institute
Molekulare und Klinische Im...
Forschung
Arbeitsgruppen
AG Schraven (Direktor)
Publikationen
Publikationen (seit 2010)
2022
Hammerschmidt SI, Thurm C, Bošnjak B, Bernhardt G, Reinhold A, Willenzon S, Ritter C, Reinhold D, Schraven B, Förster R.
Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination.
Eur J Immunol. 2022 Feb;52(2):356-359. doi: 10.1002/eji.202149645. Epub 2022 Jan 7.
Krone A, Fu Y, Schreiber S, Kotrba J, Borde L, Nötzold A, Thurm C, Negele J, Franz T, Stegemann-Koniszewski S, Schreiber J, Garbers C, Shukla A, Geffers R, Schraven B, Reinhold D, Dudeck A, Reinhold A, Müller AJ, Kahlfuss S.
Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc.
Sci Rep. 2022 Feb 4;12(1):1943. doi: 10.1038/s41598-022-04827-6.
Thurm C, Reinhold A, Borucki K, Kahlfuss S, Feist E, Schreiber J, Reinhold D, Schraven B.
Homologous and Heterologous Anti-COVID-19 Vaccination Does Not Induce New-Onset Formation of Autoantibodies Typically Accompanying Lupus Erythematodes, Rheumatoid Arthritis, Celiac Disease and Antiphospholipid Syndrome.
Vaccines (Basel). 2022 Feb 18;10(2):333. doi: 10.3390/vaccines10020333.
2021
Böning MAL, Parzmair GP, Jeron A, Düsedau HP, Kershaw O, Xu B, Relja B, Schlüter D, Dunay IR, Reinhold A, Schraven B, Bruder D.
Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function.
Front Immunol. 2021 Sep 30;12:724855. doi: 10.3389/fimmu.2021.724855. eCollection 2021. PMID: 346592
Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuß S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ.
Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.
Immunity. 2021 Oct 15:S1074-7613(21)00406-4. doi: 10.1016/j.immuni.2021.09.021. Online ahead of print.
Voss L, Guttek K, Reddig A, Reinhold A, Voss M, Simeoni L, Schraven B, Reinhold D.
Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation.
Pharmaceuticals (Basel). 2021 Jul 27;14(8):727. doi: 10.3390/ph14080727
Thurm C, Schraven B, Kahlfuss S.
ABC Transporters in T Cell-Mediated Physiological and Pathological Immune Responses.
Int J Mol Sci. 2021 Aug 25;22(17):9186. doi: 10.3390/ijms22179186.
Dadwal N, Mix C, Reinhold A, Witte A, Freund C, Schraven B, Kliche S.
The Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events.
Front Immunol. 2021 Jul 6;12:703534. doi: 10.3389/fimmu.2021.703534. eCollection 2021.
Kleinholz CL, Riek-Burchardt M, Seiß EA, Amore J, Gintschel P, Philipsen L, Bousso P, Relja B, Schraven B, Handschuh J, Mohr J, Müller AJ.
Ly6G deficiency alters the dynamics of neutrophil recruitment and pathogen capture during Leishmania major skin infection.
Sci Rep. 2021 Jul 23;11(1):15071. doi: 10.1038/s41598-021-94425-9.
Schreiber S, Hammers CM, Kaasch AJ, Schraven B, Dudeck A, Kahlfuss S.
Metabolic Interdependency of Th2 Cell-Mediated Type 2 Immunity and the Tumor Microenvironment.
Frontiers in Immunology. 2021 May 31;12:632581. doi: 10.3389/fimmu.2021.632581. eCollection 2021.
Reinhold D, Guttek K, Reddig A, Voss L, Schubert C, Kahlfuss S, Grüngreiff K, Schraven B, Reinhold A.
Zinc Aspartate Induces IL-16 Secretion and Apoptosis in Human T Cells.
Biomedicines. 2021 Mar 1;9(3):246. doi: 10.3390/biomedicines9030246.
Voss L, Guttek K, Reddig A, Reinhold A, Voss M, Schraven B, Reinhold D.
Screening of FDA-Approved Drug Library Identifies Adefovir Dipivoxil as Highly Potent Inhibitor of T Cell Proliferation.
Front Immunol. 2021 Jan 8;11:616570. doi: 10.3389/fimmu.2020.616570. eCollection 2020.
2020
Kästle M, Merten C, Hartig R, Kaehne T, Liaunardy-Jopeace A, Woessner NM, Schamel WW, James J, Minguet S, Simeoni L, Schraven B.
Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.
Cell Commun Signal. 2020 Nov 23;18(1):183. doi: 10.1186/s12964-020-00673-z. PMID: 33225946
Körtvelyessy P, Goihl A, Guttek K, Schraven B, Prüss H, Reinhold D.
Serum and CSF cytokine levels mirror different neuroimmunological mechanisms in patients with LGI1 and Caspr2 encephalitis.
Cytokine. 2020 Nov;135:155226. doi: 10.1016/j.cyto.2020.155226. Epub 2020 Aug 12.
Körtvelyessy P, Kuhle J, Düzel E, Vielhaber S, Schmidt C, Heinius A, Leypoldt F, Schraven B, Reinhold D, Leppert D, Goihl A.
Ratio and index of Neurofilament light chain indicate its origin in Guillain-Barré Syndrome.
Ann Clin Transl Neurol. 2020 Nov;7(11):2213-2220. doi: 10.1002/acn3.51207. Epub 2020 Oct 8.
Lowinus T, Bose T, Simeoni L, Schraven B, Bommhardt U.
Kv1.3 Potassium Channels: Promising Therapeutic Targets in Hematological Malignancies.
J Cell Signal. 2020, Volume 1, Issue 3
Baumann T, Dunkel A, Schmid C, Schmitt S, Hiltensperger M, Lohr K, Laketa V, Donakonda S, Ahting U, Lorenz-Depiereux B, Heil JE, Schredelseker J, Simeoni L, Fecher C, Körber N, Bauer T, Hüser N, Hartmann D, Laschinger M, Eyerich K, Eyerich S, Anton M, Streeter M, Wang T, Schraven B, Spiegel D, Assaad F, Misgeld T, Zischka H, Murray PJ, Heine A, Heikenwälder M, Korn T, Dawid C, Hofmann T, Knolle PA, Höchst B.
Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal.
Nat Immunol. 2020 May;21(5):555-566. doi: 10.1038/s41590-020-0666-9. Epub 2020 Apr 23.
Böning MAL, Trittel S, Riese P, van Ham M, Heyner M, Voss M, Parzmair GP, Klawonn F, Jeron A, Guzman CA, Jänsch L, Schraven B, Reinhold A, Bruder D.
ADAP Promotes Degranulation and Migration of NK Cells Primed During in vivo Listeria monocytogenes Infection in Mice.
Front. Immunol., 22 January 2020. https://doi.org/10.3389/fimmu.2019.03144
2019
Rudolph J, Meinke C, Voss M, Guttek K, Kliche S, Reinhold D, Schraven B, Reinhold A.
Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE.
Front Immunol. 2019 Oct 1;10:2343. doi: 10.3389/fimmu.2019.02343. eCollection 2019.
Bommhardt U, Schraven B, Simeoni L.
Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy.
Int. J. Mol. Sci. 2019, 20(14), 3500
Seiß EA, Krone A, Formaglio P, Goldmann O, Engelmann S, Schraven B, Medina E, Müller AJ.
Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils.
Sci Rep. 2019 Apr 5;9(1):5703. doi: 10.1038/s41598-019-42129-6.
Rudolph JM, Guttek K, Weitz G, Meinke CA, Kliche S, Reinhold D, Schraven B, Reinhold A.
Characterization of mice with a platelet-specific deletion of the adapter molecule ADAP.
Mol Cell Biol. 2019 Mar 4. pii: MCB.00365-18. doi: 10.1128/MCB.00365-18 . [Epub ahead of print]
Lowinus T, Heidel FH, Bose T, Nimmagadda SC, Schnöder T, Cammann C, Schmitz I, Seifert U, Fischer T, Schraven B, Bommhardt U.
Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling.
Cell Commun Signal. 2019 Jan 16;17(1):5. doi: 10.1186/s12964-018-0317-z
2018
Waldt N, Seifert A, Demiray YE, Devroe E, Turk BE, Reichardt P, Mix C, Reinhold A, Freund C, Mueller AJ, Schraven B*, Stork O*, Kliche S*.
Filamin A phosphorylation at serine 2152 by the serine/threonine kinase Ndr2 controls TCR-induced LFA-1 activation in T cells.
Front Immunol. 2018 Dec 4;9:2852. doi: 10.3389/fimmu.2018.02852. eCollection 2018.
Heyde S, Philipsen L, Formaglio P, Fu Y, Baars I, Höbbel G, Kleinholz C, Seiß EA, Stettin J, Gintschel P, Dudeck A, Bousso P, Schraven B, Müller AJ.
CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission.
PLoS Pathog. 2018 Oct 22;14(10):e1007374. doi: 10.1371/journal.ppat.1007374 . [Epub ahead of print]
Edelmann B, Gupta N, Schnöder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus RC, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller A, Fischer T.
JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
J Clin Invest. 2018 Jul 19. pii: 90312. doi: 10.1172/JCI90312
Neumann J, Henneberg S, von Kenne S, Nolte N, Müller AJ, Schraven B, Görtler MW, Reymann KG, Gunzer M, Riek-Burchardt M.
Beware the intruder: Real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivo.
PLoS One. 2018 Mar 15;13(3):e0193970.
Rheinländer A, Schraven B, Bommhardt U.
CD45 in human physiology and clinical medicine.
Immunol Lett. 2018 Jan 31;196:22-32. doi: 10.1016/j.imlet.2018.01.009 . [Epub ahead of print]
2017
Ranjan S, Goihl A, Kohli S, Gadi I, Pierau M, Shahzad K, Gupta D, Bock F, Wang H, Shaikh H, Kähne T, Reinhold D, Bank U, Zenclussen AC, Niemz J, Schnöder TM, Brunner-Weinzierl M, Fischer T, Kalinski T, Schraven B, Luft T, Huehn J, Naumann M, Heidel FH, Isermann B.
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells.
Nat Commun. 2017 Aug 21;8(1):311. doi: 10.1038/s41467-017-00169-4.
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells.
Nat Commun. 2017 Aug 21;8(1):311. doi: 10.1038/s41467-017-00169-4.
Raza SA, Albrecht A, Çaliskan G, Müller B, Demiray YE, Ludewig S, Meis S, Faber N, Hartig R, Schraven B, Lessmann V, Schwegler H, Stork O.
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience.
Nat Commun. 2017 Aug 4;8(1):189. doi: 10.1038/s41467-017-00205-3.
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience.
Nat Commun. 2017 Aug 4;8(1):189. doi: 10.1038/s41467-017-00205-3.
Thurm C, Poltorak MP, Reimer E, Brinkmann MM, Leichert L, Schraven B, Simeoni L.
A highly conserved redox-active Mx(2)CWx(6)R motif regulates Zap70 stability and activity.
Oncotarget. 2017 Mar 22. doi: 10.18632/oncotarget.16486. [Epub ahead of print]
A highly conserved redox-active Mx(2)CWx(6)R motif regulates Zap70 stability and activity.
Oncotarget. 2017 Mar 22. doi: 10.18632/oncotarget.16486. [Epub ahead of print]
Gupta N, Edelmann B, Schnoeder TM, Saalfeld FC, Wolleschak D, Kliche S, Schraven B, Heidel FH, Fischer T.
JAK2-V617F activates β1-integrin-mediated adhesion of granulocytes to vascular cell adhesion molecule 1.
Leukemia. 2017 Feb 10. doi: 10.1038/leu.2017.26. [Epub ahead of print]
JAK2-V617F activates β1-integrin-mediated adhesion of granulocytes to vascular cell adhesion molecule 1.
Leukemia. 2017 Feb 10. doi: 10.1038/leu.2017.26. [Epub ahead of print]
Parzmair GP, Gereke M, Haberkorn O, Annemann M, Podlasly L, Kliche S, Reinhold A, Schraven B, Bruder D.
ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens.
J Leukoc Biol. 2017 Feb;101(2):407-419. doi: 10.1189/jlb.1A0216-090RR.
ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens.
J Leukoc Biol. 2017 Feb;101(2):407-419. doi: 10.1189/jlb.1A0216-090RR.
Philipsen L, Reddycherla AV, Hartig R, Gumz J, Kästle M, Kritikos A, Poltorak MP, Prokazov Y, Turbin E, Weber A, Zuschratter W, Schraven B, Simeoni L, Müller AJ.
De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.
Sci Signal. 2017 Jan 17;10(462). pii: eaaf4736. doi: 10.1126/scisignal.aaf4736.
De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.
Sci Signal. 2017 Jan 17;10(462). pii: eaaf4736. doi: 10.1126/scisignal.aaf4736.
Witte A, Meineke B, Sticht J, Philipsen L, Kuropka B, Müller AJ, Freund C, Schraven B, Kliche S.
D120 and K152 within the PH domain of T cell adapter SKAP55 regulate plasma membrane targeting of SKAP55 and LFA-1 affinity modulation in human T lymphocytes.
Mol Cell Biol. 2017 Jan 4. pii: MCB.00509-16. doi: 10.1128/MCB.00509-16. [Epub ahead of print]
D120 and K152 within the PH domain of T cell adapter SKAP55 regulate plasma membrane targeting of SKAP55 and LFA-1 affinity modulation in human T lymphocytes.
Mol Cell Biol. 2017 Jan 4. pii: MCB.00509-16. doi: 10.1128/MCB.00509-16. [Epub ahead of print]
2016
Cammann C, Rath A, Reichl U, Lingel H, Brunner-Weinzierl M, Simeoni L, Schraven B, Lindquist JA.
Early changes in the metabolic profile of activated CD8(+) T cells.
BMC Cell Biol. 2016 Jul 7;17(1):28. doi: 10.1186/s12860-016-0104-x.
Early changes in the metabolic profile of activated CD8(+) T cells.
BMC Cell Biol. 2016 Jul 7;17(1):28. doi: 10.1186/s12860-016-0104-x.
Lowinus T, Bose T, Busse S, Busse M, Reinhold D, Schraven B, Bommhardt UH.
Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10777. [Epub ahead of print]
Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10777. [Epub ahead of print]
Kuropka B, Schraven B, Kliche S, Krause E, Freund C.
Expert Rev Proteomics. 2016 Jun;13(6):545-54. doi: 10.1080/14789450.2016.1187565. PMID: 27258783
Annemann M, Plaza-Sirvent C, Schuster M, Katsoulis-Dimitriou K, Kliche S, Schraven B, Schmitz I.
Atypical IκB proteins in immune cell differentiation and function.
Immunol Lett. 2016 Mar;171:26-35. doi: 10.1016/j.imlet.2016.01.006. Epub 2016 Jan 22.
Atypical IκB proteins in immune cell differentiation and function.
Immunol Lett. 2016 Mar;171:26-35. doi: 10.1016/j.imlet.2016.01.006. Epub 2016 Jan 22.
2015
Vogel S, Grabski E, Buschjäger D, Klawonn F, Döring M, Wang J, Fletcher E, Bechmann I, Witte T, Durisin M, Schraven B, Mangsbo SM, Schönfeld K, Czeloth N, Kalinke U.
Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells.
Sci Rep. 2015 Dec 16;5:18308. doi: 10.1038/srep18308.
Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells.
Sci Rep. 2015 Dec 16;5:18308. doi: 10.1038/srep18308.
Belikov AV, Schraven B, Simeoni L.
T cells and reactive oxygen species.
J Biomed Sci. 2015 Oct 15;22:85. doi: 10.1186/s12929-015-0194-3.
T cells and reactive oxygen species.
J Biomed Sci. 2015 Oct 15;22:85. doi: 10.1186/s12929-015-0194-3.
Perner F, Schnöder TM, Ranjan S, Wolleschak D, Ebert C, Pils MC, Frey S, Polanetzki A, Fahldieck C, Schönborn U, Schraven B, Isermann B, Fischer T, Heidel FH.
Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function.
Leukemia. 2015 Aug 5. doi: 10.1038/leu.2015.218. [Epub ahead of print]
Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function.
Leukemia. 2015 Aug 5. doi: 10.1038/leu.2015.218. [Epub ahead of print]
Reddycherla AV, Meinert I, Reinhold A, Reinhold D, Schraven B, Simeoni L.
miR-20a Inhibits TCR-Mediated Signaling and Cytokine Production in Human Naïve CD4+ T Cells.
PLoS One. 2015 Apr 17;10(4):e0125311. doi: 10.1371/journal.pone.0125311. eCollection 2015.
miR-20a Inhibits TCR-Mediated Signaling and Cytokine Production in Human Naïve CD4+ T Cells.
PLoS One. 2015 Apr 17;10(4):e0125311. doi: 10.1371/journal.pone.0125311. eCollection 2015.
Hasenberg A, Hasenberg M, Männ L, Neumann F, Borkenstein L, Stecher M, Kraus A, Engel DR, Klingberg A, Seddigh P, Abdullah Z, Klebow S, Engelmann S, Reinhold A, Brandau S, Seeling M, Waisman A, Schraven B, Göthert JR, Nimmerjahn F, Gunzer M.
Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.
Nat Methods. 2015 Mar 16. doi: 10.1038/nmeth.3322. [Epub ahead of print]
Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.
Nat Methods. 2015 Mar 16. doi: 10.1038/nmeth.3322. [Epub ahead of print]
Engelmann S, Togni M, Kliche S, Reinhold D, Schraven B, Reinhold A.
The adhesion- and degranulation-promoting adaptor protein and its role in the modulation of experimental autoimmune encephalomyelitis.
Crit Rev Immunol. 2015;35(1):1-14.
The adhesion- and degranulation-promoting adaptor protein and its role in the modulation of experimental autoimmune encephalomyelitis.
Crit Rev Immunol. 2015;35(1):1-14.
Neumann J, Riek-Burchardt M, Herz J, Doeppner TR, König R, Hütten H, Etemire E, Männ L, Klingberg A, Fischer T, Görtler MW, Heinze HJ, Reichardt P, Schraven B, Hermann DM, Reymann KG, Gunzer M.
Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.Acta Neuropathol.
2015 Feb;129(2):259-77. doi: 10.1007/s00401-014-1355-2. Epub 2014 Nov 13.
Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.Acta Neuropathol.
2015 Feb;129(2):259-77. doi: 10.1007/s00401-014-1355-2. Epub 2014 Nov 13.
2014
Harder T, Guttek K, Philipsen L, Simeoni L, Schraven B, Reinhold D.
Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation.
Cell Commun Signal. 2014 Dec 8;12(1):74. doi: 10.1186/s12964-014-0074-6.
Simma N, Bose T, Kahlfuß S, Mankiewicz J, Lowinus T, Lühder F, Schüler T, Schraven B, Heine M, Bommhardt U.
NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells.
Cell Commun Signal. 2014 Dec 5;12(1):75.
Belikov AV, Schraven B, Simeoni L.
TCR-triggered extracellular superoxide production is not required for T-cell activation.
Cell Commun Signal. 2014 Aug 1;12:50. doi: 10.1186/s12964-014-0050-1.
Fiedler A, Grecksch G, Reinhold A, Schraven B, Becker A.
Hippocampus-dependent learning in SKAP-HOM deficient mice.
Behav Brain Res. 2014 May 9;270C:125-130. doi: 10.1016/j.bbr.2014.04.051. [Epub ahead of print]
Wolleschak D, Mack TS, Perner F, Frey S, Schnoeder TM, Wagner MC, Höding C, Pils MC, Parkner A, Kliche S, Schraven B, Hebel K, Brunner-Weinzierl M, Ranjan S, Isermann B, Lipka DB, Fischer T, Heidel FH.
Clinically relevant doses of FLT3-kinase inhibitors Quizartinib and Midostaurin do not impair T-cell reactivity and function.
Haematologica. 2014 Mar 14. [Epub ahead of print]
Herold J, Francke A, Weinert S, Schmeisser A, Hebel K, Schraven B, Roehl FW, Strasser RH, Braun-Dullaeus RC.
Tetanus toxoid-pulsed monocyte vaccination for augmentation of collateral vessel growth.
J Am Heart Assoc. 2014 Apr 14;3(2):e000611.
Poltorak M, Meinert I, Stone JC, Schraven B, Simeoni L.
Sos1 regulates sustained TCR-mediated Erk activation.
Eur J Immunol. 2014 May;44(5):1535-40. doi: 10.1002/eji.201344046. Epub 2014 Feb 20.
Mobashir M, Madhusudhan T, Isermann B, Beyer T, Schraven B.
Negative interactions and feedback regulations are required for transient cellular response.
Sci Rep. 2014 Jan 16;4:3718. doi: 10.1038/srep03718.
2010 - 2013
Arndt B, Kalinski T, Reinhold D, Thielitz A, Roessner A, Schraven B, Simeoni L.
Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX.
J Leukoc Biol. 2013 Mar;93(3):353-62. doi: 10.1189/jlb.0312152. Epub 2013 Jan 10.
Poltorak M, Arndt B, Kowtharapu BS, Reddycherla AV, Witte V, Lindquist JA, Schraven B, Simeoni L.
TCR activation kinetics and feedback regulation in primary human T cells.
Cell Commun Signal. 2013 Jan 14;11:4. doi: 10.1186/1478-811X-11-4.
Mobashir M, Schraven B, Beyer T.
Simulated evolution of signal transduction networks.
PLoS One. 2012;7(12):e50905. doi: 10.1371/journal.pone.0050905. Epub 2012 Dec 12.
Pierau M, Na SY, Simma N, Lowinus T, Marx A, Schraven B, Bommhardt U.
Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function.
Eur J Immunol. 2012 Aug 28. doi: 10.1002/eji.201242397. [Epub ahead of print]
König S, Probst-Kepper M, Reinl T, Jeron A, Huehn J, Schraven B, Jänsch L.
First insight into the kinome of human regulatory T cells.
PLoS One. 2012;7(7):e40896. Epub 2012 Jul 16.
Warnecke N, Poltorak M, Kowtharapu BS, Arndt B, Stone JC, Schraven B, Simeoni L.
TCR-mediated Erk activation does not depend on Sos and Grb2 in peripheral human T cells.
EMBO Rep. 2012 Apr;13(4):386-91.
Togni M, Engelmann S, Reinhold D, Schraven B, Reinhold A.
The adapter protein ADAP is required for selected dendritic cell functions.
Cell Commun Signal. 2012 Jun 6;10(1):14.
Wiechec E.
Implications of genomic instability in the diagnosis and treatment of breast cancer.
Expert Rev Mol Diagn. 2011 May;11(4):445-53. Review.
Swamy M, Siegers GM, Fiala GJ, Molnar E, Dopfer EP, Fisch P, Schraven B, Schamel WW.
Stoichiometry and intracellular fate of TRIM-containing TCR complexes.
Cell Commun Signal. 2010 Mar 18;8:5.
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Rieke C, Kähne T, Schweitzer K, Schraven B, Wienands J, Engelke M, Naumann M.
Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells.
Cell Signal. 2010 Mar;22(3):395-403.
