Dr. rer. nat. Falk Lüsebrink

Medical Faculty / Dept of Neurology
Medicine and Digitalization - MedDigit
Standardized MR-Imaging; Automated Quality Control
Leipziger Straße, 44, 39120, Magdeburg, Haus 66, Raum E230   vCard

Work experience

Since 9/2018

Research associate (research focus: standardized (neurological) MR imaging, automated quality control from image to biomarkers), Workgroup Medicine and Digitalization – MedDigit, Dept. of Neurology, Otto-von-Guericke-Universität, Magdeburg, Germany


Research associate, Workgroup Biomedical Magnetic Resonance, Institute for Physics, Faculty of Natural Sciences, Otto-von-Guericke-Universität, Magdeburg, Germany


Research associate, Research group Interventional MR imaging, Forschungscampus STIMULATE, Otto-von-Guericke-Universität, Magdeburg, Germany


Educational background


PhD Student at the Faculty of Natural Sciences, Institute of Physics – Dept. of Biomedical Magnetic Resonance, Otto-von-Guericke-Universität, Magdeburg, Germany

PhD Thesis (German): “The acquisition of ultrahigh resolution magnetic resonance imaging data of the human brain in vivo and its quantitative analysis” (Summa cum laude; with highest honors)


Medical Systems Engineering (Master of Science, research focus: medical imaging and neurobiology, Otto-von-Guericke-Universität, Magdeburg, Germany

Master Thesis (German): “Cortical thickness analysis of the human brain based on high-resolution MRI data at 3 and 7 Tesla” (grade: 1,1) 


Medical Technology and Sports Medical Technology (Bachelor of Science, research focus: medical imaging), RheinAhrCampus, Remagen, Germany

Bachelor Thesis (German): “Establishment of methods for measuring cortical thickness of the human brain and their evaluation based on 7 T MRI data” (grade: 2,0)


Medicine (without degree), Ernst-Moritz-Arndt University, Greifswald, Germany


High school graduation, Anne-Frank Gymnasium, Halver, Germany



Peer-Reviewed Journal Articles 


First and Senior Authored

  1. Lüsebrink F, Sciarra A, Mattern H, Yakupov R, Speck O. T1-weighted in vivohuman whole brain MRI dataset with an ultrahigh isotropic resolution of 250 μm. Scientific Data,4:170032, 2017.
  2. Lüsebrink F, Wollrab A, Speck O. Cortical thickness determination of the human brain using high resolution 3T and 7T MRI data. NeuroImage70: 122-131, 2012.



  1. Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu KY, Priovoulos N, Fliessbach K, Dahl MJ, Maaß A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner HR, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E, Hämmerer D. Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases. Brain. 2019 Sep 1;142(9):2558-2571.
  2. Mattern H. Sciarra A, Lüsebring F, Acosta-Cabronero J, Speck O. Prospective motion correction improves high-resolution quantitative susceptibility mapping at 7T. Magn Reson Med. 2019;81:1605-1619.
  3. Mattern H, Sciarra A, Godenschweger F, Stucht D, Lüsebrink F, Rose G, Speck O. Prospective motion correction enables highest resolution time-of-flight angiography at 7T. Magn Reson Med.2018 Jul;80(1):248-258.
  4. Godenschweger F, Kägebein U, Stucht D, Yarach U, Sciarra A, Yakupov R, Lüsebrink F, Schulze P, Speck O. Motion correction in MRI of the brain. Phys Med Biol 2016 Mar 7;61(5):R32-56. doi:10.1088/0031-9155/61/5/R32
  5. Derix J, Yang S, Lüsebrink F, Fiederer L, Schulze Bonhage A, Aersten A, Speck O, Ball T. Visualization of the amygdalo-hippocampal border and its structural variability by 7T and 3T magnetic resonance imaging. Human brain mapping35 (9): 4316–4329.



Peer-Reviewed Conference Papers 


First and Senior Authored 

  1. Lüsebrink F, Mattern H, Oeltze-Jafra S, Speck O (2019). Beyond high resolution: Denoising during image reconstruction to improve image quality. ESMRMB 2019, Rotterdam, the Netherlands - Magn Reson Mater Phy (2019) 32(Suppl 1):S271-272. doi: 10.1007/s10334-019-00755-1.
  2. Lüsebrink F, Speck O (2018). Beyond high resolution: Pitfalls in quantification of cortical thickness based on higher and ultra-high resolution data. ISMRM-ESMRMB 2018, Paris, France
  3. Lüsebrink F, Mattern H, Sciarra A, Yakupov R, Speck O (2017). Ultrahoch aufgelöster T1-gewichteter in vivo MRT Datensatz des gesamten menschlichen Gehirns. Dt. Sektion der ISMRM 2017, Göttingen, Germany
  4. Lüsebrink F, Kägebein U, Speck O (2017). Conventional sequences for iMRI and their performance. Conference on Image-Guided Interventions (IGIC), Magdeburg, Germany
  5. Lüsebrink F, Speck O (2017). Beyond high resolution: Noise filtering of 250 µm T1-weighted in vivo human whole brain data to improve image quality. ESMRMB 2017, Barcelona, Spain 
  6. Lüsebrink F, Mattern H, Sciarra A, Speck O (2017). Quantitative and qualitative evaluation of bias field correction methods. ISMRM 2017, Honolulu, HI, USA
  7. Lüsebrink F, Sciarra A, Mattern H, Yakupov R, Speck O (2016). Beyond high resolution MPRAGE: In vivo T1-weighted imaging at 7T with 250 µm isotropic resolution using prospective motion correction. ISMRM 2016, Singapur, Singapur
  8. Lüsebrink F, Speck O (2014). Simultaneous contact-free monitoring of the cardiac and respiratory cycle in real-time during MRI using an optical tracking system. Interventional Magnetic Resonance Imaging (IMRI),Leipzig, Germany
  9. Lüsebrink F, Speck O (2014). Simultane Detektion des Herzschlags und der Atmung in Echtzeit im MRT mit Hilfe eines optischen Tracking-Systems. Image-Guided Interventions Conference (IGIC), Magdeburg, Germany.
  10. Lüsebrink F, Krug J, Rose G, Speck O (2014). Contact-free measurement of physiological parameters by means of an optical tracking system. Biomedizinische Technik (BMT), Hannover, Germany
  11. Lüsebrink F, Speck O (2013). Optimization of inhomogeneity correction at 7T by combining a non-parametric non-uniform intensity normalization (N3) with correction by division. ESMRMB 2013, Toulouse, France
  12. Lüsebrink F, Wollrab A, Speck O (2012). A comparison of cortical thickness determination at 3T and 7T of the human brain using high resolution data. ESMRMB 2012, Lisbon, Portugal
  13. Lüsebrink F, Wollrab A, Speck O (2010). Measuring cortical thickness of the human brain using ultra high resolution data. ISMRM-ESMRMB 2010, Stockholm, Sweden


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