Dr. med. (belg) Yannic Waerzeggers

Medical Faculty / Dept of Neurology
Medicine and Digitalization - MedDigit
Project manager
Leipziger Straße, 44, 39120, Magdeburg, Haus 66, Raum E231

Work experience

Since 7/2018

Project manager, Workgroup Medicine and Digitalization – MedDigit, Dept. for Neurology,Otto-von-Guericke-Universität, Magdeburg, Germany


Scientific project manager, European Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany

Scientific field: multimodal molecular imaging of neurodegenerative diseases


Research Assistant, Max-Planck Institute for Neurological Research, Cologne, Germany

Research field: pathophysiology of brain ischemia in feline models, neural stem cell-based gene therapy of malignant gliomas in rodent models, multimodal molecular imaging for diagnosis and therapy follow-up


Educational Background 


Medical specialist training in neurosurgery, Dept. of Neurosurgery, University Hospital UZ Leuven, Leuven, Belgium


Medical studies, Katholieke Universiteit Leuven (KUL), Leuven, Belgium


Medical studies, Limburgse Universitaire Campus (LUC), Diepenbeek, Belgium


High School graduation, Humaniora Virga Jesse, Hasselt, Belgium


Book Chapters and Series


  1. Waerzeggers Y and Jacobs AH. Animal imaging and medical challenges - cell labelling and molecular imaging. Chapter 14.4 in Textbook of in vivo Imaging in Vertebrates. Vasilis Ntziachristos, Anne Leroy-Willig, Bertrand Tavitian, editors. John Wiley & Sons, Ltd (Chichester), pp. 360-68. ISBN: 978-0-470-01528-5
  2. Jacobs AH, Waerzeggers Y, Chiocca EA, Chung J-K and Gelovani J. Imaging of Gene Therapy: Basis and Clinical Trials. Chapter 41 in Molecular Imaging: Principles and Practice. Ralph Weissleder, Brian D. Ross, Alnawaz Rehemtulla, Sanjiv Sam Gambhir, editors. McGraw-Hill Europe. ISBN-10: 1607950057
  3. Waerzeggers Y, Winkeler A and Jacobs AH. Molecular-Genetic Imaging. Chapter 28 in Molecular Imaging in Oncology. Martin G Pomper, Jouri Gelovani, editors. Informa Healthcare. pp. 443-68. ISBN: 9780849374173
  4. Waerzeggers Y, Monfared P, Winkeler A, Viel T and Jacobs AH. Imaging in Neurology Research I: Neurooncology. In: Kiessling F, Pichler BJ. Small Animal Imaging: Basics and Practical Guide. Springer 2011. ISBN 978-3-642-12945-2
  5. Waerzeggers Y, Monfared P, Ullrich R, Viel T and Jacobs AH. Impact of multimodality imaging on drug development. Chapter in Elsinga PH, van Waarde A, Paans AMJ and Dierckx RAJO. Trends on the role of PET in drug development. World Scientific Publishing Co 2012. ISBN: 978-981-4317-73-3
  6. Waerzeggers Y, Viel T, Schäfers S, Monfared P, Winkeler A, Jacobs AH. Preclinical assessment tools: imaging gene transfer to the brain. In: Cohen-Haguenauer O (Ed.) The Clinibook -  Clinical Gene Transfer: state of the art. EDK Paris 2012. ISBN: 978-2-8425-4171-2
  7. Waerzeggers Y, Zinnhardt B, Winkeler A, Monfared P, Schelhaas S,Viel T, Jacobs AH. Imaging in Neurooncology. In: Kiessling F., Pichler B. Small Animal Imaging: basics and practical guide, second edition2017; Springer, Cham: 689-725. ISBN: 978-3-319-42200-8


Peer-Reviewed Journal Articles


First and Senior Authored

  1. Waerzeggers Y, Klein M, Miletic H, Himmelreich U, Li HF, Hoehn M, Winkeler A, Jacobs AH; Multi-modal imaging of neural progenitor cell fate in rodents. Mol Imaging. 2008 Mar-Apr;7(2):77-91.
  1. Waerzeggers Y, Monfared P, Viel T, Winkeler A, Voges J, Jacobs AH. Methods to monitor gene therapy with molecular imaging. Methods. 2009 Jun;48(2):146-60.
  2. Waerzeggers Y, Monfared P, Viel T, Winkeler A, Jacobs AH. Mouse models in neurological disorders: applications of non-invasive imaging. Biochim Biophys Acta. 2010 Oct;1802(10):819-39.
  3. Waerzeggers Y, Ullrich RT, Monfared P, Viel T, Weckesser M, Stummer W, Schober O, Winkeler A, Jacobs AH. Specific biomarkers of receptors, pathways of inhibition and targeted therapies: clinical applications. Br J Radiol. 2011;84 Spec No 2:S179-95.
  4. Waerzeggers Y, Rahbar K, Riemann B, Weckesser M, Schäfers M, Hesselmann V, Niederstadt T, Willich N, Stummer W, Paulus W, Schober O, Jacobs AH. PET in the diagnosis and management of patients with brain metastasis: current role and future perspectives. Cancer Biomark. 2010;7:219-33. doi: 10.3233/CBM-2010-0200



  1. Nuttin B, Waerzeggers Y, Dom R : Treatment of elderly Parkinson patients with chronic deep brain stimulation. Tijdschrift voor Geneeskunde. 2000.
  2. Van Loon J, Waerzeggers Y, Wilms G, Van Calenbergh F, Goffin J, Plets C; Early endovascular treatment of ruptured cerebral aneurysms in patients in very poor neurological condition. Neurosurgery. 2002 Mar;50(3):457-64; discussion 464-5.
  3. Van Loon J, Waerzeggers Y, Wilms G, Van Calenbergh F, Goffin J, Plets C; Endovascular treatment for poorest-grade subarachnoid hemorrhage in the acute stage: has the outcome been improved? Neurosurgery. 2003 Feb;52(2):480-1: author reply 481-2.
  4. Goffin J, Geusens E, Vantomme N, Quintens E, Waerzeggers Y, Depreitere B, Van Calenbergh F, van Loon J; Long-term follow-up after interbody fusion of the cervical spine. J Spinal Disord Tech. 2004 Apr;17(2):79-85. 
  5. Umegaki M, Sanada Y, Waerzeggers Y, Rosner G, Yoshimine T, Heiss WD, Graf R; Peri-infarct depolarizations reveal penumbra-like conditions in striatum.
    J Neurosci. 2005 Feb 9;25(6):1387-94.
  6. Voges J, Waerzeggers Y, Maarouf M, Lehrke R, Koulousakis A, Lenartz D, Sturm V. Deep-brain stimulation: long-term analysis of complications caused by hardware and surgery - experiences from a single center. J Neurol Neurosurg Psychiatry 2006; 77;868-872.
  7. Jacobs AH, Rueger MA, Winkeler A, Li H, Vollmar S, Waerzeggers Y, Rueckriem B, Kummer C, Dittmar C, Klein M, Heneka MT, Herrlinger U, Fraefel C, Graf R, Wienhard K, Heiss WD. Imaging-Guided Gene Therapy of Experimental Gliomas. Cancer Res 2007 Feb 15; 67(4):1706-15. DOI: 10.1158/0008-5472.CAN-06-2418
  8. Miletic H, Fischer Y, Litwak S, Giroglou T, Waerzeggers Y, Winkeler A, Li H, Himmelreich U, Lange C, Stenzel W, Deckert M, Neumann H, Jacobs AH, von Laer D. Bystander Killing of Malignant Glioma by Bone Marrow-Derived Tumor Infiltrating Progenitor Cells Expressing a Suicide Gene. Mol Ther. 2007 Jul;15(7):1373-81.
  9. Winkeler A, Sena-Esteves M, Paulis LE, Li H, Waerzeggers Y, Rückriem B, Himmelreich U, Klein M, Monfared P, Rueger MA, Heneka M, Vollmar S, Hoehn M, Fraefel C, Graf R, Wienhard K, Heiss WD, Jacobs AH. Switching on the lights for gene therapy. PLoS One. 2007 Jun 13;2(6):e528.
  10. Winkeler A, Waerzeggers Y, Klose A, Monfared P, Thomas AV, Schubert M, Heneka MT, Jacobs AH. Imaging noradrenergic influence on amyloid pathology in mouse models of Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2008 Mar;35 Suppl 1:S107-13.
  11. Monfared P, Winkeler A, Klein M, Li H, Klose A, Hoesel M, Waerzeggers Y, Korsching S, Jacobs AH. Noninvasive assessment of E2F-1-mediated transcriptional regulation in vivo. Cancer Res. 2008 Jul 15;68(14):5932-40. doi: 10.1158/0008-5472.CAN-07-6373
  12. Ullrich RT, Zander T, Neumaier B, Koker M, Shimamura T, Waerzeggers Y, Borgman CL, Tawadros S, Li H, Sos ML, Backes H, Shapiro GI, Wolf J, Jacobs AH, Thomas RK, Winkeler A. Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET). PLoS One. 2008;3(12):e3908.
  13. Klose A, Waerzeggers Y, Monfared P, Vukicevic S, Kaijzel EL, Winkeler A, Wickenhauser C, Löwik CW, Jacobs AH. Imaging bone morphogenetic protein 7 induced cell cycle arrest in experimental gliomas. Neoplasia. 2011 Mar;13(3):276-85.
  14. Viel T, Talasila KM, Monfared P, Wang J, Jikeli JF, Waerzeggers Y, Neumaier B, Backes H, Brekka N, Thorsen F, Stieber D, Niclou SP, Winkeler A, Tavitian B, Hoehn M, Bjerkvig R, Miletic H, Jacobs AH. Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI.J Nucl Med. 2012;53:1135-45. jnumed.111.101659v1

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